Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 5/20 | 0.41 |
| ▸ | CES2 | O00748 | 3/20 | 0.39 |
| ▸ | CES1 | P23141 | 3/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.38 |
| ▸ | PPARG | P37231 | 6/20 | 0.38 |
| ▸ | PPARD | Q03181 | 6/20 | 0.38 |
| ▸ | PPARA | Q07869 | 6/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TLR2 | O60603 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | FABP4 | P15090 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11766669 | 0.91 | DNM1 (0.46) | DNM1CES2CES1GPR84PPARG | |
| SCHEMBL25481592 | 0.91 | ALDH1A1 (0.39) | DNM1CES2CES1ALDH1A1 | |
| SCHEMBL15997772 | 0.89 | DNM1 (0.42) | DNM1CES2CES1 | |
| SCHEMBL21880763 | 0.87 | DNM1 (0.46) | DNM1ALDH1A1 | |
| SCHEMBL18596717 | 0.87 | DNM1 (0.46) | DNM1ALDH1A1 | |
| SCHEMBL17936461 | 0.84 | DNM1 (0.42) | DNM1CES2CES1ALDH1A1 | |
| SCHEMBL24211068 | 0.84 | CES2 (0.41) | DNM1CES2CES1GPR84PPARG | |
| SCHEMBL25093997 | 0.84 | EPHX2 (0.41) | DNM1CES2CES1 | |
| SCHEMBL22986134 | 0.83 | DNM1 (0.34) | DNM1CES2CES1MEN1KMT2A | |
| SCHEMBL25770730 | 0.83 | EPHX2 (0.40) | DNM1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11110160-B2 | Glycoconjugation processes and compositions | PFIZER INC. (US) | 2021-09-07 | — | — | US | disclosed |
| US-20200246448-A1 | GLYCOCONJUGATION PROCESSES AND COMPOSITIONS | PFIZER INC. | 2020-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11110160-B2 | Glycoconjugation processes and compositions | GNE, SIGLEC7, SIGLEC9 | DNM1 2707/4885CES2 818/4885CES1 1256/4885 |
| US-20200246448-A1 | GLYCOCONJUGATION PROCESSES AND COMPOSITIONS | GNE, SIGLEC7, SIGLEC9 | DNM1 2707/4885CES2 818/4885CES1 1256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.