Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 2/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.33 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25781207 | 0.93 | CYP4F2 (0.37) | CYP4F2CYP4A11MCL1GRM5NOTUM | |
| SCHEMBL25772189 | 0.89 | CYP4F2 (0.38) | CYP4F2CYP4A11NPC1L3MBTL1S1PR5 | |
| SCHEMBL25773868 | 0.86 | CCR5 (0.35) | CYP4F2CYP4A11MCL1NOTUMS1PR5 | |
| SCHEMBL25772187 | 0.83 | FNTA (0.35) | GRM5 | |
| SCHEMBL25781205 | 0.82 | CYP4F2 (0.39) | CYP4F2CYP4A11MCL1NOTUMS1PR5 | |
| SCHEMBL25772194 | 0.80 | RORC (0.38) | CYP4F2CYP4A11SMN1; SMN2MCL1S1PR5 | |
| SCHEMBL25771371 | 0.79 | OXER1 (0.51) | — | |
| SCHEMBL25783329 | 0.79 | OXER1 (0.51) | — | |
| SCHEMBL25771372 | 0.79 | OXER1 (0.51) | — | |
| SCHEMBL25774793 | 0.78 | OXER1 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023115203-A1 | OXER1 ANTAGONISTS AND USES THEREOF | FAIRHAVEN PHARMACEUTICALS INC. (CA) | 2023-06-29 | — | — | WO | disclosed |