SCHEMBL25774574

SCHEMBL25774574

CCCCCCCCCCCCCCCCCCC[C@H](COP(=O)(O)OC1[C@@]2(C)O[C@@H](c3ccc4c(N)ncnn34)[C@H](O)[C@@]12O)OCc1ccc(C#N)c(Cl)c1

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ POLRMT O00411 1/20 0.34
▸ PIK3CD O00329 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25077230 0.93 POLRMT (0.34) POLRMTPIK3CD
SCHEMBL25077000 0.93 POLRMT (0.34) POLRMTPIK3CD
SCHEMBL25077573 0.93 POLRMT (0.34) POLRMTPIK3CD
SCHEMBL25770080 0.90 POLRMT (0.35) POLRMT
SCHEMBL25770098 0.90 POLRMT (0.35) POLRMT
SCHEMBL25077541 0.90 POLRMT (0.35) POLRMT
SCHEMBL25774275 0.89 POLRMT (0.35) POLRMT
SCHEMBL25077160 0.88 POLRMT (0.38) POLRMT
SCHEMBL25077199 0.88 POLRMT (0.41) POLRMTPIK3CD
SCHEMBL25076999 0.88 POLRMT (0.34) POLRMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230212199-A1 PHOSPHOLIPID COMPOUNDS AND METHODS OF MAKING AND USING THE SAME GILEAD SCIENCES, INC. 2023-07-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230212199-A1 PHOSPHOLIPID COMPOUNDS AND METHODS OF MAKING AND USING THE SAME PHOSPHO1, SGMS1, SGMS2 POLRMT 266/4885PIK3CD 246/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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