Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 2/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | USP1 | O94782 | 7/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2574521 | 0.91 | USP1 (0.32) | MGLLUSP1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2577512 | 0.90 | PTGDR2 (0.37) | PTGDR2MGLLFAAHUSP1NPC1 | |
| SCHEMBL2572487 | 0.86 | PTGDR2 (0.53) | PTGDR2MGLLFAAHUSP1 | |
| SCHEMBL2576049 | 0.84 | PTGDR2 (0.37) | PTGDR2 | |
| SCHEMBL3666571 | 0.84 | PTGDR2 (0.53) | PTGDR2MGLLFAAHUSP1 | |
| SCHEMBL2576429 | 0.83 | PTGDR2 (0.44) | PTGDR2MGLLFAAHUSP1 | |
| SCHEMBL2574519 | 0.81 | USP1 (0.33) | MGLLUSP1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2572499 | 0.78 | PTGDR2 (0.44) | PTGDR2MGLLUSP1 | |
| SCHEMBL534061 | 0.76 | AR (0.36) | PTGDR2SMN1; SMN2 | |
| SCHEMBL2572975 | 0.76 | PTGDR2 (0.38) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139881-B1 | QUINOLINES AND THEIR THERAPEUTIC USE | PULMAGEN THERAPEUTICS ASTHMA LTD (GB) | 2011-11-09 | — | — | EP | claimed |