Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.32 |
| ▸ | MBOAT4 | Q96T53 | 2/20 | 0.32 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.31 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL533987 | 0.89 | AR (0.36) | ARCYP19A1MBOAT4SLC5A1SLC5A2 | |
| SCHEMBL534060 | 0.88 | AR (0.36) | ARPTGDR2MBOAT4GAASMN1; SMN2 | |
| SCHEMBL533928 | 0.85 | AR (0.40) | ARCYP19A1LOXL2 | |
| SCHEMBL534048 | 0.83 | PTGDR2 (0.49) | ARPTGDR2 | |
| SCHEMBL2579398 | 0.82 | PTGDR2 (0.34) | PTGDR2 | |
| SCHEMBL534798 | 0.81 | PTGDR2 (0.41) | ARPTGDR2 | |
| SCHEMBL534921 | 0.81 | PTGDR2 (0.49) | ARPTGDR2CYP19A1 | |
| SCHEMBL2572975 | 0.80 | PTGDR2 (0.38) | PTGDR2MBOAT4 | |
| SCHEMBL2577516 | 0.76 | PTGDR2 (0.37) | PTGDR2SMN1; SMN2 | |
| SCHEMBL533986 | 0.76 | AR (0.36) | ARMBOAT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2129661-B1 | QUINOLINE DERIVATIVES AS CRTH2 RECEPTOR LIGANDS | PULMAGEN THERAPEUTICS ASTHMA LTD (GB) | 2012-02-08 | — | — | EP | claimed |