Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | RXRB | P28702 | 1/20 | 0.49 |
| ▸ | RXRG | P48443 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 3/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.48 |
| ▸ | LIPE | Q05469 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.43 |
| ▸ | EDNRA | P25101 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2579088 | 0.81 | MAPT (0.59) | MAPTL3MBTL1TDP1MAPK1RXRA | |
| SCHEMBL25680974 | 0.79 | MAPT (0.56) | MAPTL3MBTL1TDP1MAPK1RXRA | |
| SCHEMBL14279390 | 0.77 | MAPT (0.53) | MAPTL3MBTL1TDP1MAPK1RXRA | |
| SCHEMBL265584 | 0.76 | MAPK1 (0.70) | MAPTL3MBTL1TDP1MAPK1RXRA | |
| SCHEMBL29874217 | 0.76 | MAPK1 (0.70) | MAPTL3MBTL1TDP1MAPK1RXRA | |
| SCHEMBL13748188 | 0.76 | MAPK1 (0.40) | MAPTL3MBTL1TDP1MAPK1RXRA | |
| SCHEMBL8497192 | 0.76 | MAPT (0.65) | MAPTL3MBTL1TDP1MAPK1RXRA | |
| Acetic Acid SCHEMBL28238681 | 0.76 | RXRA (0.73) | MAPTL3MBTL1TDP1MAPK1RXRA | |
| SCHEMBL12708729 | 0.75 | ABCG2 (0.42) | MAPTMAPK1LMNAKDM4EALDH1A1 | |
| SCHEMBL2880443 | 0.75 | MAPT (0.81) | MAPTL3MBTL1TDP1MAPK1RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2399585-A1 | Boronic acids and esters as inhibitors of fatty acid amide hydrolase | Infinity Pharmaceuticals, Inc. (US) | 2011-12-28 | — | — | EP | disclosed |