Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.70 |
| ▸ | MAPT | P10636 | 1/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | RXRA | P19793 | 1/20 | 0.69 |
| ▸ | RXRB | P28702 | 1/20 | 0.69 |
| ▸ | RXRG | P48443 | 1/20 | 0.69 |
| ▸ | LIPE | Q05469 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 5/20 | 0.57 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.57 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.57 |
| ▸ | SCN4A | P35499 | 2/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29874217 | 1.00 | MAPK1 (0.70) | MAPK1MAPTTDP1L3MBTL1RXRA | |
| SCHEMBL3764673 | 0.93 | RXRA (0.71) | MAPK1MAPTTDP1L3MBTL1RXRA | |
| Acetic Acid SCHEMBL28238681 | 0.91 | RXRA (0.73) | MAPK1MAPTTDP1L3MBTL1RXRA | |
| SCHEMBL28014706 | 0.88 | RXRA (0.66) | MAPK1MAPTTDP1L3MBTL1RXRA | |
| SCHEMBL7606605 | 0.88 | RXRA (0.65) | MAPK1MAPTTDP1L3MBTL1RXRA | |
| SCHEMBL1703348 | 0.88 | RXRA (0.65) | MAPK1MAPTTDP1L3MBTL1RXRA | |
| Isobutane SCHEMBL27820518 | 0.86 | RXRA (0.68) | MAPK1MAPTTDP1L3MBTL1RXRA | |
| SCHEMBL12301137 | 0.86 | RXRA (0.63) | MAPK1MAPTTDP1L3MBTL1RXRA | |
| SCHEMBL2880443 | 0.86 | MAPT (0.81) | MAPK1MAPTTDP1L3MBTL1RXRA | |
| SCHEMBL12301123 | 0.86 | RXRA (0.63) | MAPK1MAPTTDP1L3MBTL1RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 218 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2104685-A | — | — | None | — | — | JP | disclosed |
| WO-2024005461-A1 | NOVEL LINKER COMPOUND AND LIGAND-DRUG CONJUGATE THEREFOR | 주식회사 트리오어 | 2024-01-04 | — | — | WO | disclosed |
| US-11664093-B2 | Extrapolative prediction of enantioselectivity enabled by computer-driven workflow, new molecular representations and machine learning | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2023-05-30 | — | — | US | disclosed |
| US-20230151159-A1 | COMPOUND FOR FORMING HARDMASK, HARDMASK COMPOSITION INCLUDING THE COMPOUND, AND METHOD OF MANUFACTURING INTEGRATED CIRCUIT DEVICE USING THE HARDMASK COMPOSITION | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2023-05-18 | — | — | US | disclosed |
| WO-2022140316-A1 | SUBSTITUTED MACROCYCLIC COMPOUNDS AND RELATED METHODS OF TREATMENT | ALKERMES, INC. (US) | 2022-06-30 | — | — | WO | disclosed |
| US-20220177451-A1 | 1-CYANO-PYRROLIDINE DERIVATIVES AS DUB INHIBITORS | MISSION THERAPEUTICS LIMITED (GB) | 2022-06-09 | — | — | US | disclosed |
| US-11352339-B2 | 1-cyano-pyrrolidine derivatives as DUB inhibitors | MISSION THERAPEUTICS LIMITED (GB) | 2022-06-07 | — | — | US | disclosed |
| EP-3433246-B1 | 1-CYANO-PYRROLIDINE DERIVATIVES AS DBU INHIBITORS | MISSION THERAPEUTICS LTD (GB) | 2022-05-04 | — | — | EP | disclosed |
| US-11273168-B2 | Methods of treating anxiety by administering a substituted quinolone | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2022-03-15 | — | — | US | disclosed |
| EP-3380471-B1 | TETRAHYDRO-8H-PYRIDO[1,2-A]PYRAZINE-8-ONES AS COMT INHIBITORS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | LIEBER INST INC DBA LIEBER INST FOR BRAIN DEVELOPMENT (US) | 2021-09-08 | — | — | EP | disclosed |
| US-5117062-A | Aromatic tertiary amines, enamines, deoxybenzoins and benzils | HAY ALLAN S (CA) | 1992-05-26 | — | — | US | disclosed |
| EP-0460679-A2 | Endothelin antagonistic peptide derivatives | Banyu Pharmaceutical Co., Ltd. (JP) | 1991-12-11 | — | — | EP | disclosed |
| US-5011998-A | Aromatic tertiary amines, enamines, deoxybenzoins and benzils | HAY ALLAN S (CA) | 1991-04-30 | — | — | US | disclosed |
| JP-H02104685-A | NOVEL 2-BENZYLOXYBENZALDEHYDE DIALKYLACETAL AND ITS PRODUCTION | BASF AG | 1990-04-17 | — | — | JP | disclosed |
| EP-0355754-A2 | 2-Benzyloxybenzaldehyde dialkyl acetals, their preparation and use | BASF Aktiengesellschaft (DE) | 1990-02-28 | — | — | EP | disclosed |
| US-4200717-A | Preparation of propylene polymer-containing solid titanium trichloride and propylene polymers using same | MITSUBISHI CHEMICAL INDUSTRIES, LTD. (JP) | 1980-04-29 | — | — | US | disclosed |
| US-4115532-A | LEWIS ACIDS, HEATING, PRECIPITATION | MITSUBISHI CHEMICAL INDUSTRIES, LTD. (JP) | 1978-09-19 | — | — | US | disclosed |
| US-4115533-A | REDUCING TITANIUM TETRACHLORIDE WITH AN ORGANIC ALUMINUM COMPOUND | MITSUBISHI CHEMICAL INDUSTRIES, LTD. (JP) | 1978-09-19 | — | — | US | disclosed |
| US-4060593-A | Preparation of titanium trichloride | MITSUBISHI CHEMICAL INDUSTRIES (JA) | 1977-11-29 | — | — | US | disclosed |
| US-3968320-A | Dye solvents for pressure-sensitive record material | MONSANTO COMPANY (US) | 1976-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11273168-B2 | Methods of treating anxiety by administering a substituted quinolone | CRH, MC2R, HTR3C | MAPK1 1767/4885MAPT 3210/4885TDP1 2750/4885 |
| US-11352339-B2 | 1-cyano-pyrrolidine derivatives as DUB inhibitors | USP30, USP28, USP1 | MAPK1 1970/4885MAPT 3074/4885TDP1 1839/4885 |
| US-20220177451-A1 | 1-CYANO-PYRROLIDINE DERIVATIVES AS DUB INHIBITORS | USP30, USP28, USP1 | MAPK1 1970/4885MAPT 3074/4885TDP1 1839/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.