Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 3/20 | 0.37 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25775979 | 0.92 | MAOA (0.42) | KMT2AMAOAMAOBALDH1A1HTT | |
| SCHEMBL25776127 | 0.74 | MAOB (0.40) | KMT2AMAOAMAOBALDH1A1HTT | |
| SCHEMBL25780148 | 0.74 | HPGD (0.41) | MEN1KMT2ALMNAHRH3ALDH1A1 | |
| SCHEMBL18126615 | 0.71 | OXER1 (0.41) | MEN1KMT2AMAOAMAOBTAAR1 | |
| SCHEMBL8093810 | 0.71 | TAAR1 (0.65) | HRH3TAAR1NAAA | |
| SCHEMBL8101532 | 0.71 | TAAR1 (0.65) | HRH3TAAR1NAAA | |
| SCHEMBL8094389 | 0.71 | TAAR1 (0.65) | HRH3TAAR1NAAA | |
| SCHEMBL8100077 | 0.71 | TAAR1 (0.65) | HRH3TAAR1NAAA | |
| SCHEMBL8101372 | 0.71 | TAAR1 (0.65) | HRH3TAAR1NAAA | |
| SCHEMBL8095693 | 0.71 | TAAR1 (0.65) | HRH3TAAR1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023115203-A1 | OXER1 ANTAGONISTS AND USES THEREOF | FAIRHAVEN PHARMACEUTICALS INC. (CA) | 2023-06-29 | — | — | WO | disclosed |