Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25775975 | 0.87 | HPGD (0.44) | HPGDHTTHSD17B10KMT2AMEN1 | |
| SCHEMBL25780218 | 0.86 | HPGD (0.36) | HPGDHTTHSD17B10KMT2AMEN1 | |
| SCHEMBL25780241 | 0.77 | MYC (0.37) | HPGDHTTHSD17B10KMT2AMEN1 | |
| SCHEMBL25780149 | 0.77 | HPGD (0.37) | HPGDHTTHSD17B10KMT2AMEN1 | |
| SCHEMBL25775979 | 0.74 | MAOA (0.42) | HPGDHTTKMT2AKDM4EALDH1A1 | |
| SCHEMBL25776140 | 0.74 | CYP1A2 (0.40) | HPGDHTTKMT2AMEN1LMNA | |
| SCHEMBL31369943 | 0.74 | SLC1A3 (0.42) | HPGDHTTHSD17B10KMT2AMEN1 | |
| SCHEMBL30731237 | 0.71 | HSD17B10 (0.47) | HPGDHTTHSD17B10KMT2AMEN1 | |
| SCHEMBL25783244 | 0.69 | IRAK4 (0.41) | — | |
| SCHEMBL25775977 | 0.68 | HSD17B10 (0.47) | HPGDHTTHSD17B10KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023115203-A1 | OXER1 ANTAGONISTS AND USES THEREOF | FAIRHAVEN PHARMACEUTICALS INC. (CA) | 2023-06-29 | — | — | WO | disclosed |