Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 2/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | OTUD7B | Q6GQQ9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17611616 | 1.00 | FFAR3 (0.37) | FFAR3HTTMETAP2GRIN1GRIN2A | |
| SCHEMBL23388900 | 0.88 | GRIN1 (0.35) | FFAR3HTTGRIN1GRIN2A | |
| SCHEMBL24108397 | 0.83 | METAP2 (0.31) | METAP2OTUD7B | |
| SCHEMBL18039796 | 0.78 | SMN1; SMN2 (0.37) | METAP2 | |
| SCHEMBL29215936 | 0.78 | METAP2 (0.35) | METAP2 | |
| SCHEMBL25667128 | 0.78 | — | — | |
| SCHEMBL25667077 | 0.77 | — | — | |
| SCHEMBL19327287 | 0.76 | LMNA (0.39) | GRIN1GRIN2AGRIN2B | |
| SCHEMBL19327285 | 0.76 | LMNA (0.39) | GRIN1GRIN2AGRIN2B | |
| SCHEMBL19331557 | 0.74 | POLB (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116877-A1 | HETEROCYCLIC COMPOUND AS TEAD INHIBITOR | 武汉人福创新药物研发中心有限公司 | 2023-06-29 | — | — | WO | disclosed |
| CN-116332922-A | Heterocyclic compounds as TEAD inhibitors | 武汉人福创新药物研发中心有限公司 | 2023-06-27 | — | — | CN | disclosed |
| WO-2023049199-A1 | AZOLE COMPOUNDS | ZENO MANAGEMENT, INC. (US) | 2023-03-30 | — | — | WO | disclosed |