Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | CHUK | O15111 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 2/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CCND1 | P24385 | 1/20 | 0.35 |
| ▸ | CCNC | P24863 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | CDK7 | P50613 | 1/20 | 0.35 |
| ▸ | CCNH | P51946 | 1/20 | 0.35 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.35 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.35 |
| ▸ | GRK2 | P25098 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25786281 | 0.80 | GRM2 (0.42) | PRKCIDYRK1ARIPK1IKBKBCHUK | |
| SCHEMBL25235562 | 0.77 | PRKCI (0.42) | PRKCIDYRK1ARIPK1IKBKBCHUK | |
| SCHEMBL17998720 | 0.76 | DYRK1A (0.41) | DYRK1AIKBKBCHUKJAK3CIT | |
| SCHEMBL17998756 | 0.75 | JAK1 (0.46) | JAK3JAK1 | |
| SCHEMBL24117359 | 0.74 | ADORA2A (0.35) | PRKCIDYRK1ANUDT1CIT | |
| SCHEMBL17998718 | 0.74 | ADORA2A (0.46) | PRKCIDYRK1AJAK3JAK2LMNA | |
| SCHEMBL25242649 | 0.73 | PRKCI (0.36) | PRKCIDYRK1ARIPK1IKBKBCHUK | |
| SCHEMBL21915045 | 0.73 | LMNA (0.41) | PRKCIDYRK1AJAK3JAK2NUDT1 | |
| SCHEMBL681636 | 0.73 | DYRK1A (0.34) | PRKCIDYRK1AJAK3JAK2NUDT1 | |
| SCHEMBL25238351 | 0.72 | LMNA (0.35) | PRKCIDYRK1ARIPK1IKBKBCHUK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116779-A1 | DIALKYNE COMPOUND AND USE THEREOF | 上海艾力斯医药科技股份有限公司 | 2023-06-29 | — | — | WO | disclosed |