Metabutoxycaine

Metabutoxycaine

SCHEMBL25778

CCCCOc1c(N)cccc1C(=O)OCCN(CC)CC

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.58
HSD17B10 Q99714 2/20 0.58
SCN1A P35498 7/20 0.58
SCN2A Q99250 7/20 0.58
SCN3A Q9NY46 7/20 0.58
TSHR P16473 6/20 0.58
CYP2D6 P10635 5/20 0.58
CYP1A2 P05177 4/20 0.58
HRH3 Q9Y5N1 4/20 0.58
KCNH2 Q12809 3/20 0.58
SLC6A2 P23975 1/20 0.58
SLC6A3 Q01959 1/20 0.58
HIF1A Q16665 1/20 0.58
RAD52 P43351 1/20 0.57
KDM4E B2RXH2 2/20 0.52
POLB P06746 1/20 0.52
MAOA P21397 3/20 0.50
HTR3A P46098 3/20 0.50
CYP3A4 P08684 3/20 0.50
CHRM2 P08172 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Metabutoxycaine SCHEMBL1643491 0.99 RAD52 (0.58) ALDH1A1HSD17B10SCN1ASCN2ASCN3A
Metabutoxycaine SCHEMBL30053144 0.99 RAD52 (0.58) ALDH1A1HSD17B10SCN1ASCN2ASCN3A
SCHEMBL5710554 0.83 SCN1A (0.62) ALDH1A1HSD17B10SCN1ASCN2ASCN3A
Metabutoxycaine SCHEMBL17261288 0.83 SCN1A (0.55) ALDH1A1HSD17B10SCN1ASCN2ASCN3A
SCHEMBL4644788 0.82 SCN1A (0.66) ALDH1A1HSD17B10SCN1ASCN2ASCN3A
SCHEMBL10710678 0.78 ALDH1A1 (0.74) ALDH1A1HSD17B10SCN1ASCN2ASCN3A
SCHEMBL27629621 0.78 SCN1A (0.58) ALDH1A1HSD17B10SCN1ASCN2ASCN3A
SCHEMBL10519506 0.77 SCN1A (0.61) ALDH1A1HSD17B10SCN1ASCN2ASCN3A
Ambucaine SCHEMBL82280 0.77 SCN1A (0.91) ALDH1A1HSD17B10SCN1ASCN2ASCN3A
SCHEMBL11339945 0.76 ALDH1A1 (0.62) ALDH1A1HSD17B10SCN1ASCN2ASCN3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2416 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144801-A1 COMPOSITIONS AND METHODS FOR PREVENTING OR TREATING MUSCLE CONDITIONS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2026-05-28 US claimed
US-20260115156-A1 INJECTABLE COMPOSITION INCLUDING HYDROGEL CONTAINING ANESTHETIC AGENT UNIV KOREA RES & BUS FOUND (KR) 2026-04-30 US claimed
WO-2025235864-A1 COATED NEEDLE ADMINISTRATION SYSTEMS EVOLUS, INC. (US) 2025-11-13 WO claimed
US-20250332183-A1 COMPOSITIONS AND METHODS FOR THE STIMULATION OF INTERMEDIATE MACROPHAGES AND TREATMENTS THEREWITH AYUVIS RESEARCH, INC. 2025-10-30 US claimed
US-20250319025-A9 COMPOSITIONS COMPRISING MODIFIED PHOSPHOLIPIDS AND USES THEREOF THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 2025-10-16 US claimed
EP-4578441-A1 TREATMENT OF LOCALIZED PAIN PlantTec Medical GmbH (DE) 2025-07-02 EP claimed
US-20250205278-A1 METHODS AND COMPOSITIONS FOR WOUND HEALING ABBOTT NICHOLAS L (US) 2025-06-26 US claimed
WO-2025128639-A1 HYDROGELS COMPRISING PROTEIN-STABILIZED NANOPARTICLES FOR EXTENDED RELEASE THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 2025-06-19 WO claimed
US-12329856-B2 Crosslinked hyaluronic acid composition with local anesthetics BIOPOLIMERI S.R.L. (IT) 2025-06-17 US claimed
US-20250186364-A1 COMBINATION OF ANTISPASMODIC AND ANESTHETIC AGENTS FOR TOPICAL PRODUCTS AND THEIR METHOD OF USE PRIMA INNOVATIONS, LLC 2025-06-12 US claimed
EP-1027015-A1 CONTROLLED RELEASE OF PHARMACEUTICALS IN THE ANTERIOR CHAMBER OF THE EYE Galin, Miles A. (US) 2000-08-16 EP claimed
CN-1251979-A Controlled release of drugs in the anterior chamber of the eye MILES A GALIN (US) 2000-05-03 CN claimed
US-5972326-A Controlled release of pharmaceuticals in the anterior chamber of the eye IOLTECH (FR) 1999-10-26 US claimed
US-5939425-A ANALGESICS ADMINISTERED BY INHALATION ALGOS PHARMACEUTICAL CORPORATION (US) 1999-08-17 US claimed
EP-0932416-A2 METHOD AND POTENTIATED COMPOSITION FOR TREATING MIGRAINE Algos Pharmaceutical Corporation (US) 1999-08-04 EP claimed
WO-1998041171-A1 CONTROLLED RELEASE OF PHARMACEUTICALS IN THE ANTERIOR CHAMBER OF THE EYE GALIN MILES A (US) 1998-09-24 WO claimed
US-5776952-A Method and composition for topical therapy of back pain and muscle tension AMERICAN PHARMED LABS, INC. (US) 1998-07-07 US claimed
WO-1998015275-A2 METHOD AND POTENTIATED COMPOSITION FOR TREATING MIGRAINE ALGOS PHARMACEUTICAL CORPORATION (US) 1998-04-16 WO claimed
US-5209724-A Buffering local anesthetic, reducing pain and irritation on injection M.D., INC. 1993-05-11 US claimed
US-5149320-A Using parenteral solution containing sodium bicarbonate and dissolved carbon dioxide M.D., INC. 1992-09-22 US claimed