Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CES2 | O00748 | 2/20 | 0.32 |
| ▸ | CES1 | P23141 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7262131 | 0.84 | TPMT (0.38) | TPMTALDH1A1TSHRPARP1CA1 | |
| SCHEMBL2964828 | 0.82 | TSHR (0.43) | TPMTALDH1A1TSHRCES2CES1 | |
| SCHEMBL4725617 | 0.82 | ALDH1A1 (0.36) | TPMTALDH1A1TSHRPARP1CA1 | |
| SCHEMBL31226955 | 0.82 | TSHR (0.43) | ALDH1A1TSHRPARP1CES2CES1 | |
| SCHEMBL16675516 | 0.82 | ESR1 (0.47) | TPMTALDH1A1TSHRCA1CA2 | |
| SCHEMBL4727563 | 0.82 | TPMT (0.37) | TPMTALDH1A1TSHRPARP1CA1 | |
| SCHEMBL789006 | 0.80 | CES2 (0.43) | ALDH1A1TSHRPARP1CES2CES1 | |
| SCHEMBL17135281 | 0.80 | CES2 (0.43) | TPMTALDH1A1TSHRCES2CES1 | |
| SCHEMBL22501562 | 0.80 | ALDH1A1 (0.36) | TPMTALDH1A1TSHRPARP1CA1 | |
| SCHEMBL19545230 | 0.80 | MAPT (0.37) | TPMTALDH1A1TSHRCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023124736-A1 | X-RAY DEVELOPABLE MOLECULE, X-RAY DEVELOPABLE EMBOLIC MICROSPHERE AND PREPARATION METHOD THEREFOR | 上海汇禾医疗科技有限公司 | 2023-07-06 | — | — | WO | disclosed |
| CN-111138498-B | Application of disubstituted aromatic acid modified Anderson polyacid as coxsackie virus inhibitor | 湖北工业大学 | 2022-10-04 | — | — | CN | disclosed |
| CN-111821503-B | Radiopaque high-efficiency drug-loaded embolism microsphere and preparation and application thereof | 苏州恒瑞宏远医疗科技有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-111821503-A | Radiopaque high-efficiency drug-loaded embolism microsphere and preparation and application thereof | 苏州恒瑞宏远医疗科技有限公司 | 2020-10-27 | — | — | CN | disclosed |
| CN-111138498-A | Application of disubstituted aromatic acid modified Anderson polyacid as coxsackie virus inhibitor | 湖北工业大学 | 2020-05-12 | — | — | CN | disclosed |