SCHEMBL25780

SCHEMBL25780

CN(C)CCOCC[O]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7988561 0.97 CA12 (0.47)
SCHEMBL15091 0.85 CA12 (0.52)
SCHEMBL7777517 0.84 ALDH1A1 (0.41)
SCHEMBL4396393 0.84 CA12 (0.41)
SCHEMBL28731355 0.82 CA12 (0.44)
SCHEMBL12918862 0.82 CA12 (0.56)
Hydrochloric Acid SCHEMBL473385 0.82 CA12 (0.50)
SCHEMBL31696969 0.82 CA12 (0.50)
Water SCHEMBL2217898 0.82 CA12 (0.50)
SCHEMBL3973874 0.82 CA12 (0.56)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7196 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11970711-B2 Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-04-30 US claimed
EP-4314297-A1 TARGETING ONCOGENTIC MUTATIONS WITH DUAL-CLEAVING ENDONUCLEASE Specific Biologics Inc. (CA) 2024-02-07 EP claimed
WO-2024013361-A1 OLIGONUCLEOTIDES FOR ADAR-MEDIATED RNA EDITING AND USE THEREOF PROQR THERAPEUTICS II B.V. (NL) 2024-01-18 WO claimed
CN-117083385-A Targeting oncogenic mutations with double-cleaving endonucleases 特定生物制品公司 2023-11-17 CN claimed
US-11795472-B2 RNA-guided nucleic acid modifying enzymes and methods of use thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-10-24 US claimed
WO-2023201203-A2 CRISPR-CAS EFFECTOR POLYPEPTIDES AND METHODS OF USE THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-10-19 WO claimed
EP-4240839-A1 GENE EDITING WITH A MODIFIED ENDONUCLEASE Specific Biologics Inc. (CA) 2023-09-13 EP claimed
CN-116669775-A Gene editing with modified endonucleases 特定生物制品公司 2023-08-29 CN claimed
WO-2023152371-A1 GUIDE OLIGONUCLEOTIDES FOR NUCLEIC ACID EDITING IN THE TREATMENT OF HYPERCHOLESTEROLEMIA PROQR THERAPEUTICS II B.V. (NL) 2023-08-17 WO claimed
WO-2023107531-A2 ANTISENSE OLIGONUCLEOTIDE DRUG TARGETS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2023-06-15 WO claimed
US-20020147198-A1 Substituted arylamine derivatives and methods of use AMGEN INC. 2002-10-10 US claimed
WO-2002068406-A2 SUBSTITUTED AMINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF ANGIOGENESIS AMGEN INC. (US) 2002-09-06 WO claimed
WO-2002066470-A1 SUBSTITUTED ALKYLAMINE DERIVATIVES AND METHODS OF USE AMGEN INC. (US) 2002-08-29 WO claimed
WO-2002055501-A2 N-PYRIDYL CARBOXAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AMGEN INC (US) 2002-07-18 WO claimed
WO-2002032864-A1 PHARMACEUTICALLY ACTIVE SULFANILIDE DERIVATIVES APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) 2002-04-25 WO claimed
US-20020049173-A1 Alteration of cellular behavior by antisense modulation of mRNA processing ISIS PHARMACEUTICALS, INC. 2002-04-25 US claimed
WO-2001072765-A1 ALTERATION OF CELLULAR BEHAVIOR BY ANTISENSE MODULATION OF mRNA PROCESSING ISIS PHARMACEUTICALS, INC. (US) 2001-10-04 WO claimed
WO-2001052902-A1 ANTISENSE MODULATION OF INDUCIBLE NITRIC OXIDE SYNTHASE EXPRESSION ISIS PHARMACEUTICALS, INC. (US) 2001-07-26 WO claimed
US-6210892-B1 HYBRIDIZING AN ANTISENSE COMPOUND HAVING A 2' SUGAR, MORPHOLINO, OR PEPTIDE NUCLEIC ACID MODIFICATION TO TARGET MESSENGER RNA TO CHANGE ITS PROCESSING INCLUDING SPLICING, POLYADENYLATION OR STABILITY ISIS PHARMACEUTICALS, INC. 2001-04-03 US claimed
US-4917989-A MULTILAYER; TRANSPARENT SUBSTRATE, DYE AND REFLECTOR BASF AKTIENGESELLSCHAFT (DE) 1990-04-17 US claimed