Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25780 | 0.97 | — | — | |
| SCHEMBL3973874 | 0.86 | CA12 (0.56) | CA12CA1CA2CA9USP2 | |
| SCHEMBL12918862 | 0.86 | CA12 (0.56) | CA12CA1CA2CA9USP2 | |
| SCHEMBL28731355 | 0.85 | CA12 (0.44) | CA12CA1CA2CA9USP2 | |
| Ammonia Solution, Strong SCHEMBL17238502 | 0.83 | CA12 (0.54) | CA12CA1CA2CA9USP2 | |
| SCHEMBL15091 | 0.83 | CA12 (0.52) | CA12CA1CA2CA9USP2 | |
| SCHEMBL7777517 | 0.82 | ALDH1A1 (0.41) | CHRM2CHRM4CHRM5CHRM1CHRNB2 | |
| SCHEMBL4396393 | 0.82 | CA12 (0.41) | CA12CA1CA2CA9USP2 | |
| SCHEMBL31696969 | 0.80 | CA12 (0.50) | CA12CA1CA2CA9USP2 | |
| Hydrochloric Acid SCHEMBL473385 | 0.80 | CA12 (0.50) | CA12CA1CA2CA9USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115515637-A | Mixed therapy using IL-20 antagonists and immune checkpoint inhibitors | 永福生物科技股份有限公司 | 2022-12-23 | — | — | CN | disclosed |
| CN-106661105-B | Treatment of inflammatory pain with IL-20 antagonists | 永福生物科技股份有限公司 | 2022-07-19 | — | — | CN | disclosed |
| CN-108026533-B | Antagonistic PDL1 aptamers and their use in cancer therapy | 中央研究院 | 2021-08-17 | — | — | CN | disclosed |
| CN-112654706-A | Nucleic acid aptamers targeting lymphocyte activation gene 3(LAG-3) and uses thereof | 合一生技股份有限公司 | 2021-04-13 | — | — | CN | disclosed |
| CN-112567037-A | TNF targeting aptamer for treating or diagnosing TNF related inflammatory diseases and application thereof | 中央研究院 | 2021-03-26 | — | — | CN | disclosed |
| CN-105899238-B | Treatment of hepatitis virus infection by modulation of microRNAMIR-130 a, miR-130b, miR-204 or miR-1236 | 中央研究院 | 2021-02-26 | — | — | CN | disclosed |
| CN-111108121-A | Use of IL-20 antagonists for treating ocular diseases | 永福生物科技股份有限公司 | 2020-05-05 | — | — | CN | disclosed |
| CN-110997002-A | Targeting HDAC2-SP3 complexes to enhance synaptic function | 麻省理工学院 | 2020-04-10 | — | — | CN | disclosed |
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |