Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 7/20 | 0.56 |
| ▸ | RAB9A | P51151 | 7/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2578011 | 1.00 | FBP1 (0.57) | FBP1NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL28303080 | 0.77 | RAB9A (0.53) | FBP1NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL2578813 | 0.76 | FBP1 (0.53) | FBP1NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL2580094 | 0.76 | FBP1 (0.53) | FBP1NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL2578810 | 0.76 | FBP1 (0.53) | FBP1NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL28155610 | 0.73 | FBP1 (0.50) | FBP1NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL491094 | 0.73 | FBP1 (1.00) | FBP1MAPTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL491095 | 0.73 | FBP1 (1.00) | FBP1MAPTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL12357033 | 0.72 | MAPT (0.60) | NPC1RAB9AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL3183983 | 0.72 | MAPT (0.54) | FBP1NPC1RAB9AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385034-A2 | Process for the preparation of 1-nitro-4-oxobutanylamides | Synkola, s.r.o. (SK) | 2011-11-09 | — | — | EP | disclosed |