SCHEMBL257830

SCHEMBL257830

CCCOc1c(C)cc(F)cc1Br

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.40
KMT2A Q03164 6/20 0.40
ALDH1A1 P00352 5/20 0.40
MAPT P10636 4/20 0.40
L3MBTL1 Q9Y468 4/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
HPGD P15428 1/20 0.39
HTT P42858 1/20 0.39
KDM4E B2RXH2 4/20 0.38
LMNA P02545 3/20 0.38
TDP1 Q9NUW8 1/20 0.38
RAB9A P51151 1/20 0.38
ATM Q13315 1/20 0.38
MCL1 Q07820 1/20 0.37
THRA P10827 4/20 0.37
THRB P10828 4/20 0.37
GAA P10253 1/20 0.35
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13144437 0.91 THRA (0.46) MEN1KMT2AALDH1A1MAPTL3MBTL1
SCHEMBL31550351 0.91 MAPT (0.44) MEN1KMT2AALDH1A1MAPTL3MBTL1
SCHEMBL27283667 0.91 MAPT (0.44) MEN1KMT2AALDH1A1MAPTL3MBTL1
SCHEMBL21777805 0.89 MAPT (0.49) MEN1KMT2AALDH1A1MAPTL3MBTL1
SCHEMBL27283032 0.83 ATM (0.37) MEN1KMT2AALDH1A1MAPTL3MBTL1
SCHEMBL12269067 0.82 ALDH1A1 (0.40) MEN1KMT2AALDH1A1MAPTL3MBTL1
SCHEMBL12440969 0.81 MAPT (0.56) MEN1KMT2AALDH1A1MAPTL3MBTL1
SCHEMBL13429874 0.81 ALDH1A1 (0.39) MEN1KMT2AALDH1A1MAPTL3MBTL1
SCHEMBL15039627 0.79 MAPT (0.39) MEN1KMT2AALDH1A1MAPTSMN1; SMN2
SCHEMBL28452195 0.79 SCN8A (0.31) THRATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115038725-B Polymerization process comprising group III and lanthanide bis-phenyl-phenoxy metal-ligand complexes and chain transfer agents 陶氏环球技术有限责任公司 2024-06-14 CN disclosed
CN-115298227-B Group III and lanthanide bis-phenyl-phenoxy metal-ligand complexes 陶氏环球技术有限责任公司 2024-06-04 CN disclosed
CN-117069749-A Group III and lanthanide bis-phenyl-phenoxy metal-ligand complexes 陶氏环球技术有限责任公司 2023-11-17 CN disclosed
CN-112585172-B Diphenyl phenoxy polyolefin procatalyst with two anthracene ligands 陶氏环球技术有限责任公司 2023-05-23 CN disclosed
CN-115298227-A Group III and lanthanide bis-phenyl-phenoxy metal-ligand complexes 陶氏环球技术有限责任公司 2022-11-04 CN disclosed
CN-115038725-A Polymerization process comprising group III and lanthanide bis-phenyl-phenoxy metal-ligand complexes and chain transfer agents 陶氏环球技术有限责任公司 2022-09-09 CN disclosed
CN-112585172-A Bis-phenylphenoxy polyolefin procatalysts with two anthracene-based ligands 陶氏环球技术有限责任公司 2021-03-30 CN disclosed
EP-2399585-A1 Boronic acids and esters as inhibitors of fatty acid amide hydrolase Infinity Pharmaceuticals, Inc. (US) 2011-12-28 EP disclosed
EP-2399584-A1 Boronic acids and esters as inhibitors of fatty acid amide hydrolase Infinity Pharmaceuticals, Inc. (US) 2011-12-28 EP disclosed