Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25782854 | 0.82 | S1PR1 (0.40) | S1PR1S1PR5NOTUMBCHEMEN1 | |
| SCHEMBL25782990 | 0.76 | NR4A2 (0.43) | BCHE | |
| SCHEMBL25783158 | 0.75 | S1PR1 (0.40) | S1PR1S1PR5NOTUMMEN1KMT2A | |
| SCHEMBL25782852 | 0.74 | TSHR (0.38) | KDM4EMEN1KMT2A | |
| SCHEMBL25783157 | 0.73 | S1PR1 (0.39) | S1PR1S1PR5NOTUMMEN1KMT2A | |
| SCHEMBL25772307 | 0.73 | CYP4F2 (0.37) | S1PR1S1PR5NOTUMMEN1KMT2A | |
| SCHEMBL25783159 | 0.71 | S1PR1 (0.39) | S1PR1S1PR5NOTUMBCHEMEN1 | |
| SCHEMBL25782959 | 0.71 | KMT2A (0.46) | BCHEKDM4EMEN1KMT2ATDP1 | |
| SCHEMBL25772437 | 0.70 | S1PR1 (0.38) | S1PR1S1PR5NOTUMMEN1KMT2A | |
| SCHEMBL25782743 | 0.64 | THRA (0.53) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023115203-A1 | OXER1 ANTAGONISTS AND USES THEREOF | FAIRHAVEN PHARMACEUTICALS INC. (CA) | 2023-06-29 | — | — | WO | disclosed |