Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 7/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.44 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.36 |
| ▸ | SELE | P16581 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14396817 | 0.89 | SOS1 (0.54) | HTR2ASLC6A4KCNH2SOS1DRD2 | |
| SCHEMBL14396803 | 0.88 | HTR2A (0.51) | HTR2ASLC6A4KCNH2SOS1DRD2 | |
| SCHEMBL257824 | 0.87 | KDM4E (0.46) | HTR2ASLC6A4KCNH2SOS1HSP90AA1 | |
| SCHEMBL12260824 | 0.86 | HTR2A (0.40) | HTR2ASLC6A4KCNH2SOS1DRD2 | |
| SCHEMBL257852 | 0.86 | SOS1 (0.50) | HTR2ASLC6A4KCNH2SOS1LMNA | |
| SCHEMBL4371877 | 0.85 | NPC1 (0.46) | HTR2ASLC6A4KCNH2SOS1CYP3A4 | |
| SCHEMBL10269964 | 0.84 | HTR2A (0.40) | HTR2ASLC6A4KCNH2SOS1DRD2 | |
| SCHEMBL14649910 | 0.82 | HSP90AA1 (0.57) | HTR2ASLC6A4KCNH2DRD2DRD4 | |
| SCHEMBL8736417 | 0.80 | TEAD4 (0.48) | HTR2ASLC6A4KCNH2DRD2DRD4 | |
| SCHEMBL675954 | 0.80 | HTR2A (0.54) | HTR2ASLC6A4KCNH2SOS1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2399585-A1 | Boronic acids and esters as inhibitors of fatty acid amide hydrolase | Infinity Pharmaceuticals, Inc. (US) | 2011-12-28 | — | — | EP | disclosed |