Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29447829 | 0.96 | PDK2 (0.41) | PDK2LMNATP53POLBAPEX1 | |
| SCHEMBL10233458 | 0.96 | PDK2 (0.41) | PDK2LMNATP53POLBAPEX1 | |
| SCHEMBL20411189 | 0.94 | POLB (0.42) | PDK2LMNATP53POLBAPEX1 | |
| SCHEMBL24469748 | 0.92 | PDK2 (0.40) | PDK2LMNATP53POLBAPEX1 | |
| SCHEMBL25784469 | 0.92 | L3MBTL1 (0.39) | PDK2LMNATP53POLBAPEX1 | |
| SCHEMBL25784463 | 0.90 | PDK2 (0.37) | PDK2LMNATP53POLBAPEX1 | |
| SCHEMBL22648236 | 0.88 | PDK2 (0.35) | PDK2LMNATP53POLBAPEX1 | |
| SCHEMBL30800968 | 0.87 | POLB (0.48) | PDK2LMNATP53POLBAPEX1 | |
| SCHEMBL157502 | 0.87 | POLB (0.48) | PDK2LMNATP53POLBAPEX1 | |
| SCHEMBL25784675 | 0.87 | THRB (0.47) | PDK2LMNATP53POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3966195-B1 | FLUORENE DERIVATIZED MONOMERS AND POLYMERS FOR VOLUME BRAGG GRATINGS | FACEBOOK TECH LLC (US) | 2023-07-05 | — | — | EP | disclosed |