SCHEMBL257849

SCHEMBL257849

Cc1ccc(OC(C)c2ccccc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.54
ALOX5 P09917 1/20 0.51
LTB4R Q15722 8/20 0.48
LTB4R2 Q9NPC1 8/20 0.48
IGLV6-57 P01721 1/20 0.48
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
S1PR5 Q9H228 2/20 0.46
S1PR1 P21453 1/20 0.46
KCNH2 Q12809 1/20 0.44
SCN3A Q9NY46 1/20 0.44
ADRA2A P08913 1/20 0.42
ADRA2B P18089 1/20 0.42
ADRA2C P18825 1/20 0.42
PPARG P37231 1/20 0.41
PPARA Q07869 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6904351 0.91 FFAR1 (0.61) FFAR1ALOX5LTB4RLTB4R2IGLV6-57
SCHEMBL4363303 0.87 FFAR1 (0.56) FFAR1ALOX5LTB4RLTB4R2IGLV6-57
SCHEMBL13951559 0.83 ALDH1A1 (0.55) FFAR1ALOX5LTB4RLTB4R2S1PR5
SCHEMBL14268020 0.83 ALOX5 (0.55) FFAR1ALOX5LTB4RLTB4R2IGLV6-57
SCHEMBL11853864 0.83 FFAR1 (0.54) FFAR1ALOX5LTB4RLTB4R2S1PR5
SCHEMBL15474267 0.83 PTGS1 (0.53) FFAR1ALOX5IGLV6-57MEN1KMT2A
SCHEMBL15474268 0.83 PTGS1 (0.53) FFAR1ALOX5IGLV6-57MEN1KMT2A
SCHEMBL8157398 0.82 SLC6A4 (0.53) FFAR1ALOX5LTB4RLTB4R2NPSR1
SCHEMBL12260858 0.82 FFAR1 (0.53) FFAR1ALOX5LTB4RLTB4R2IGLV6-57
SCHEMBL12190647 0.82 IGLV6-57 (0.47) FFAR1ALOX5LTB4RLTB4R2IGLV6-57

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112334319-A Thermosensitive recording material 王子控股株式会社 2021-02-05 CN disclosed
EP-2399585-A1 Boronic acids and esters as inhibitors of fatty acid amide hydrolase Infinity Pharmaceuticals, Inc. (US) 2011-12-28 EP disclosed
EP-2399584-A1 Boronic acids and esters as inhibitors of fatty acid amide hydrolase Infinity Pharmaceuticals, Inc. (US) 2011-12-28 EP disclosed
US-7494537-B2 Thermochromic coloring color-memory composition and thermochromic coloring color-memory microcapsule pigment containing the same THE PILOT INK CO., LTD. (JP) 2009-02-24 US disclosed
EP-0486745-A1 Improved solvents for chromogens useful in the manufacture of carbonless copying paper MONSANTO EUROPE S.A./N.V. (BE) 1992-05-27 EP disclosed
US-3968320-A Dye solvents for pressure-sensitive record material MONSANTO COMPANY (US) 1976-07-06 US disclosed