⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21402240 | 0.76 | PIK3CB (0.46) | — | |
| SCHEMBL25818049 | 0.70 | GRIN2B (0.31) | — | |
| SCHEMBL25786302 | 0.69 | ALDH1A1 (0.32) | — | |
| SCHEMBL18125587 | 0.69 | MEN1 (0.36) | — | |
| SCHEMBL26596983 | 0.69 | BACE1 (0.35) | — | |
| SCHEMBL20674122 | 0.69 | AOC3 (0.36) | — | |
| SCHEMBL16302839 | 0.69 | GRIN2B (0.39) | — | |
| SCHEMBL12575038 | 0.67 | RPS6KA5 (0.52) | — | |
| SCHEMBL18125595 | 0.67 | PIK3CB (0.38) | — | |
| SCHEMBL18125584 | 0.67 | MEN1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122298-A1 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP28 AND/OR USP25 TARGETING LIGANDS | Stablix, Inc. (US) | 2023-06-29 | — | — | WO | disclosed |