Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PI4KA | P42356 | 1/20 | 0.32 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.32 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4282443 | 0.75 | KDM4E (0.32) | ALDH1A1KDM4E | |
| SCHEMBL12775631 | 0.72 | HDAC6 (0.37) | ALDH1A1KDM4ENPC1MAPTRAB9A | |
| SCHEMBL25786299 | 0.69 | — | — | |
| SCHEMBL2618032 | 0.67 | ALDH1A1 (0.38) | ALDH1A1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL24910096 | 0.66 | NPC1 (0.34) | ALDH1A1KDM4ENPC1MAPTRAB9A | |
| SCHEMBL12410751 | 0.64 | LTA4H (0.35) | ALDH1A1KDM4ENPC1MAPTRAB9A | |
| SCHEMBL14871073 | 0.63 | KDM4E (0.36) | ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL23476802 | 0.63 | NPC1 (0.37) | ALDH1A1KDM4ENPC1MAPTRAB9A | |
| SCHEMBL24995633 | 0.62 | PI4KA (0.38) | ALDH1A1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL976444 | 0.62 | PI4KA (0.41) | ALDH1A1NPC1RAB9API4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122298-A1 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP28 AND/OR USP25 TARGETING LIGANDS | Stablix, Inc. (US) | 2023-06-29 | — | — | WO | disclosed |