Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ME2 | P23368 | 1/20 | 0.65 |
| ▸ | ME1 | P48163 | 1/20 | 0.65 |
| ▸ | ME3 | Q16798 | 1/20 | 0.65 |
| ▸ | CA12 | O43570 | 1/20 | 0.64 |
| ▸ | CA2 | P00918 | 1/20 | 0.64 |
| ▸ | CA9 | Q16790 | 1/20 | 0.64 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.61 |
| ▸ | CCR1 | P32246 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.55 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL762466 | 0.86 | MAPT (0.58) | ME2ME1ME3CA12CA2 | |
| SCHEMBL14895193 | 0.86 | ME2 (0.60) | ME2ME1ME3CA12CA2 | |
| SCHEMBL945056 | 0.85 | ME2 (0.65) | ME2ME1ME3CA12CA2 | |
| SCHEMBL3767729 | 0.84 | ME2 (0.60) | ME2ME1ME3CA12CA2 | |
| SCHEMBL14895098 | 0.84 | CNR1 (0.59) | ME2ME1ME3CA12CA2 | |
| SCHEMBL12041849 | 0.84 | ME2 (0.64) | ME2ME1ME3CA12CA2 | |
| SCHEMBL4507048 | 0.84 | ME2 (0.56) | ME2ME1ME3MAPTMAPK1 | |
| SCHEMBL31642475 | 0.83 | POLB (0.73) | MAPTALDH1A1POLBCYP2C19 | |
| SCHEMBL12781894 | 0.83 | POLB (0.73) | MAPTALDH1A1POLBCYP2C19 | |
| SCHEMBL12041848 | 0.83 | RAB9A (0.61) | ME2ME1ME3CA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3805214-B1 | JAK3 SELECTIVE INHIBITOR | UNIV PEKING SHENZHEN GRADUATE SCHOOL (CN) | 2023-07-05 | — | — | EP | disclosed |