SCHEMBL2578946

SCHEMBL2578946

CCc1ccc(Cc2ccccc2O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1

nearest known ligand 0.82

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ SLC5A2 P31639 20/20 0.82
▸ SLC5A1 P13866 12/20 0.79

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4356546 1.00 SLC5A2 (0.82) SLC5A2SLC5A1
SCHEMBL4356542 1.00 SLC5A2 (0.82) SLC5A2SLC5A1
SCHEMBL2576270 0.91 SLC5A2 (0.79) SLC5A2SLC5A1
SCHEMBL4350700 0.90 SLC5A2 (1.00) SLC5A2SLC5A1
SCHEMBL2577336 0.90 SLC5A2 (1.00) SLC5A2SLC5A1
SCHEMBL1037900 0.90 SLC5A2 (0.81) SLC5A2SLC5A1
SCHEMBL2575165 0.90 SLC5A2 (0.81) SLC5A2SLC5A1
SCHEMBL12807952 0.90 SLC5A2 (0.67) SLC5A2SLC5A1
SCHEMBL2576286 0.89 SLC5A2 (0.80) SLC5A2SLC5A1
SCHEMBL2583297 0.89 SLC5A2 (0.80) SLC5A2SLC5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8048897-B2 Cyclohexane derivative, prodrug thereof and salt thereof, and therapeutic agent containing the same for diabetes CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2011-11-01 — — US claimed
US-20080318874-A1 Novel Cyclohexane Derivative, Prodrug Thereof and Salt Thereof, and Therapeutic Agent Containing the Same for Diabetes CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2008-12-25 — — US claimed
EP-1783110-A1 NOVEL CYCLOHEXANE DERIVATIVE, PRODRUG THEREOF AND SALT THEREOF, AND THERAPEUTIC AGENT CONTAINING THE SAME FOR DIABETES CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2007-05-09 — — EP claimed
EP-1782828-B1 PROGRESSION INHIBITOR FOR DISEASE ATTRIBUTED TO ABNORMAL ACCUMULATION OF LIVER FAT KISSEI PHARMACEUTICAL (JP) 2016-06-29 — — EP disclosed
US-8048897-B2 Cyclohexane derivative, prodrug thereof and salt thereof, and therapeutic agent containing the same for diabetes CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2011-11-01 — — US disclosed
US-20080318874-A1 Novel Cyclohexane Derivative, Prodrug Thereof and Salt Thereof, and Therapeutic Agent Containing the Same for Diabetes CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2008-12-25 — — US disclosed
US-7465712-B2 Glucopyranosyloxy benzylbenzene derivatives, medicinal compositions containing the same and intermediates for the preparation of the derivatives KISSEI PHARMACEUTICAL CO., LTD. (JP) 2008-12-16 — — US disclosed
US-7465712-B2 Glucopyranosyloxy benzylbenzene derivatives, medicinal compositions containing the same and intermediates for the preparation of the derivatives KISSEI PHARMACEUTICAL CO., LTD. (JP) 2008-12-16 — — US disclosed
US-7465712-B2 Glucopyranosyloxy benzylbenzene derivatives, medicinal compositions containing the same and intermediates for the preparation of the derivatives KISSEI PHARMACEUTICAL CO., LTD. (JP) 2008-12-16 — — US disclosed
EP-1783110-A1 NOVEL CYCLOHEXANE DERIVATIVE, PRODRUG THEREOF AND SALT THEREOF, AND THERAPEUTIC AGENT CONTAINING THE SAME FOR DIABETES CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2007-05-09 — — EP disclosed
EP-1782828-A1 PROGRESSION INHIBITOR FOR DISEASE ATTRIBUTED TO ABNORMAL ACCUMULATION OF LIVER FAT Kissei Pharmaceutical Co., Ltd. (JP) 2007-05-09 — — EP disclosed
US-6872706-B2 Glucopyranosyloxybenzylbenzene derivatives and medicinal compositions containing the same KISSEI PHARMACEUTICAL CO., LTD. (JP) 2005-03-29 — — US disclosed
US-20050065098-A1 Glucopyranosyloxybenzylbenzene derivatives and medicinal compositions containing the same KISSEI PHARMACEUTICAL CO., LTD. 2005-03-24 — — US disclosed
CN-1177857-C Glucopyranosyloxy benzylbenzene derivatives, medicinal compositions containing the same and intermediates for the prepararation of the derivatives ����ҩƷ��ҵ��ʽ���� 2004-12-01 — — CN disclosed
US-20040053855-A1 Glucopyranosyloxy benzylbenzene derivatives, medicinal compositions containing the same and intermediates for the preparation of the derivatives KISSEI PHARMACEUTICAL CO & LTD. (JP) 2004-03-18 — — US disclosed
US-20040018998-A1 Glucopyranosyloxybenzylbenzene derivatives and medicinal compositions containing the same KISSEI PHARMACEUTICAL CO., LTD. (JP) 2004-01-29 — — US disclosed
CN-1466590-A Glucopyranosyloxybenzylbenzene derivatives and medicinal compositions containing the same ����ҩƷ��ҵ��ʽ���� 2004-01-07 — — CN disclosed
EP-1329456-A1 GLUCOPYRANOSYLOXYBENZYLBENZENE DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME Kissei Pharmaceutical Co., Ltd. (JP) 2003-07-23 — — EP disclosed
CN-1418219-A Glucopyranosyloxy benzylbenzene derivatives, medicinal compositions containing the same and intermediates for the prepararation of the derivatives KISSEI PHARMACEUTICAL (JP) 2003-05-14 — — CN disclosed
EP-1270584-A1 GLUCOPYRANOSYLOXY BENZYLBENZENE DERIVATIVES, MEDICINAL COMPOSITIONS CONTAINING THE SAME AND INTERMEDIATES FOR THE PREPARATION OF THE DERIVATIVES Kissei Pharmaceutical Co., Ltd. (JP) 2003-01-02 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040053855-A1 Glucopyranosyloxy benzylbenzene derivatives, medicinal compositions containing the same and intermediates for the preparation of the derivatives SLC5A2, SLC5A1, SLC2A2 SLC5A2 1/4885SLC5A1 2/4885
US-20050065098-A1 Glucopyranosyloxybenzylbenzene derivatives and medicinal compositions containing the same SLC5A2, SLC5A1, SLC2A2 SLC5A2 1/4885SLC5A1 2/4885
US-20080318874-A1 Novel Cyclohexane Derivative, Prodrug Thereof and Salt Thereof, and Therapeutic Agent Containing the Same for Diabetes SLC5A1, GPR119, SLC5A2 SLC5A2 3/4885SLC5A1 1/4885
US-20040018998-A1 Glucopyranosyloxybenzylbenzene derivatives and medicinal compositions containing the same SLC5A2, SLC5A1, SLC2A1 SLC5A2 1/4885SLC5A1 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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