Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | CRHBP | P24387 | 1/20 | 0.56 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.56 |
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.55 |
| ▸ | PARP14 | Q460N5 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | F10 | P00742 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.53 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL257857 | 0.84 | MEN1 (0.58) | MEN1KMT2AHTTGAAHPGD | |
| SCHEMBL753990 | 0.84 | MEN1 (0.58) | MEN1KMT2AHTTGAAHPGD | |
| SCHEMBL757027 | 0.84 | MEN1 (0.58) | MEN1KMT2AHTTGAAMAPT | |
| SCHEMBL903593 | 0.82 | MAPT (0.85) | MEN1KMT2AHTTMAPTCRHBP | |
| SCHEMBL8738334 | 0.82 | PARP14 (0.78) | MEN1KMT2AHTTMAPTCRHBP | |
| SCHEMBL903429 | 0.81 | KMT2A (0.85) | MEN1KMT2AHTTHPGDMAPT | |
| SCHEMBL2536884 | 0.81 | L3MBTL1 (0.76) | MEN1KMT2AHTTGAAHPGD | |
| SCHEMBL3455749 | 0.80 | KMT2A (0.60) | MEN1KMT2AHTTGAAHPGD | |
| SCHEMBL14601259 | 0.80 | PARP10 (0.67) | HTTMAPTCRHBPCRHR2PARP10 | |
| SCHEMBL14277718 | 0.80 | PARP14 (0.69) | MEN1KMT2AHTTMAPTCRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2399585-A1 | Boronic acids and esters as inhibitors of fatty acid amide hydrolase | Infinity Pharmaceuticals, Inc. (US) | 2011-12-28 | — | — | EP | disclosed |