SCHEMBL2579003

SCHEMBL2579003

CC(C)(C)OC(=O)N(CCN(CC(=O)O)C(=O)OC(C)(C)C)CC(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA14 Q9ULX7 2/20 0.42
HDAC6 Q9UBN7 2/20 0.36
HDAC1 Q13547 2/20 0.36
HDAC2 Q92769 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
EYA2 O00167 1/20 0.36
APP P05067 1/20 0.36
ACE P12821 1/20 0.36
BLM P54132 2/20 0.34
PMP22 Q01453 2/20 0.34
ADRA1A P35348 2/20 0.34
KDM4E B2RXH2 1/20 0.34
LMNA P02545 1/20 0.34
CHRM2 P08172 1/20 0.34
ADRA2A P08913 1/20 0.34
ALOX15 P16050 1/20 0.34
TSHR P16473 1/20 0.34
DRD1 P21728 1/20 0.34
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10388977 0.93 CA14 (0.39) CA14HDAC6HDAC1HDAC2TDP1
SCHEMBL78691 0.91 CA14 (0.41) CA14HDAC6HDAC1HDAC2TDP1
SCHEMBL5916355 0.90 CA14 (0.43) CA14HDAC6HDAC1HDAC2TDP1
SCHEMBL22852725 0.90 CA14 (0.43) CA14HDAC6HDAC1HDAC2TDP1
SCHEMBL1677637 0.90 CA12 (0.40) CA14HDAC6HDAC1HDAC2TDP1
SCHEMBL11521511 0.89 CA14 (0.39) CA14HDAC6HDAC1HDAC2TDP1
SCHEMBL10786935 0.89 CA14 (0.39) CA14HDAC6HDAC1HDAC2TDP1
SCHEMBL18631244 0.89 CA14 (0.39) CA14HDAC6HDAC1HDAC2TDP1
SCHEMBL16280777 0.88 CA14 (0.39) CA14HDAC6HDAC1HDAC2TDP1
SCHEMBL19339624 0.87 CA14 (0.38) CA14HDAC6HDAC1HDAC2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1699491-B1 BRANCHED POLYETHYLENE GLYCOL FOR LINKING POLYMER RESIDUES TO ANTIBODIES UCB PHARMA SA (BE) 2011-11-16 EP disclosed
US-7736635-B2 Branched molecular scaffolds for linking polymer residues to biologically active moieties UCB PHARMA S.A. (BE) 2010-06-15 US disclosed
US-20070128150-A1 Branched molecular scaffolds for linking polymer residues to biologically active moieties UCB BIOPHARMA SPRL (BE) 2007-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070128150-A1 Branched molecular scaffolds for linking polymer residues to biologically active moieties ILK, ECPAS, FGB CA14 1343/4885HDAC6 1096/4885HDAC1 1184/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.