Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 3/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.43 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | CCR8 | P51685 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 3/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | LYN | P07948 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20047458 | 0.83 | PDK2 (0.32) | PDK2PDK4CNR2 | |
| SCHEMBL25928008 | 0.80 | PAK4 (0.35) | PDK2PDK4CNR2 | |
| SCHEMBL23502433 | 0.77 | CNR2 (0.33) | CNR2 | |
| SCHEMBL12240432 | 0.76 | PDK2 (0.44) | PDK2PDK4SSTR4CCR1CCR5 | |
| SCHEMBL15481077 | 0.76 | EGLN2 (0.38) | DRD2 | |
| SCHEMBL31110275 | 0.73 | NOS3 (0.52) | PDK2PDK4SSTR4CCR1CCR5 | |
| SCHEMBL18072068 | 0.73 | NOS3 (0.52) | PDK2PDK4SSTR4CCR1CCR5 | |
| SCHEMBL25896493 | 0.72 | OPRK1 (0.36) | OPRK1CCR1CCR5CCR8NOS3 | |
| SCHEMBL25790850 | 0.72 | OPRK1 (0.31) | OPRK1 | |
| SCHEMBL19083788 | 0.71 | SSTR4 (0.45) | PDK2PDK4SSTR4OPRK1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125928-A1 | MENIN INHIBITOR AND USE THEREOF | 成都先导药物开发股份有限公司 | 2023-07-06 | — | — | WO | disclosed |