Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MERTK | Q12866 | 7/20 | 0.39 |
| ▸ | AXL | P30530 | 6/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2400337 | 0.89 | LMNA (0.45) | MAPK1TSHRSMN1; SMN2MERTKAXL | |
| SCHEMBL2400321 | 0.89 | LMNA (0.45) | MAPK1TSHRSMN1; SMN2MERTKAXL | |
| SCHEMBL6413448 | 0.88 | ALDH1A1 (0.42) | ALDH1A1MAPK1MEN1KMT2APOLB | |
| SCHEMBL2401835 | 0.86 | MERTK (0.42) | ALDH1A1MAPTMERTKAXLMET | |
| SCHEMBL2401891 | 0.86 | MEN1 (0.42) | ALDH1A1MEN1KMT2AMERTKAXL | |
| SCHEMBL2400825 | 0.86 | POLB (0.41) | ALDH1A1POLBSMN1; SMN2MERTKAXL | |
| SCHEMBL2402565 | 0.85 | MERTK (0.42) | ALDH1A1MERTKAXLMETTYRO3 | |
| SCHEMBL2403325 | 0.84 | KCNA5 (0.51) | ALDH1A1MEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL6411128 | 0.82 | MERTK (0.44) | MERTKAXLMETTYRO3P2RX7 | |
| SCHEMBL2403572 | 0.82 | KMT2A (0.41) | ALDH1A1MEN1KMT2AGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8048890-B2 | Analgesics; neuropathic pain; headaches; muscle relaxants; incontence; tinnitus; diarrhea; antiarrhythmia agents; antiischemic agents; antiinflammatory agents; antiulcer agents; antidepressants; antiepileptic agents | GRUENENTHAL GMBH (DE) | 2011-11-01 | — | — | US | disclosed |