Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.59 |
| ▸ | RECQL | P46063 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | RXRA | P19793 | 8/20 | 0.48 |
| ▸ | RARA | P10276 | 5/20 | 0.48 |
| ▸ | RARB | P10826 | 5/20 | 0.48 |
| ▸ | RARG | P13631 | 5/20 | 0.48 |
| ▸ | RXRB | P28702 | 3/20 | 0.48 |
| ▸ | RXRG | P48443 | 3/20 | 0.48 |
| ▸ | RORC | P51449 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | HTR2B | P41595 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10952287 | 0.96 | ALDH1A1 (0.52) | ALDH1A1ALOX15RECQLHSD17B10TDP1 | |
| SCHEMBL10952289 | 0.96 | ALDH1A1 (0.52) | ALDH1A1ALOX15RECQLHSD17B10TDP1 | |
| SCHEMBL28352153 | 0.96 | ALDH1A1 (0.52) | ALDH1A1ALOX15RECQLHSD17B10TDP1 | |
| SCHEMBL9665397 | 0.83 | ALDH1A1 (0.54) | ALDH1A1ALOX15RECQLHSD17B10TDP1 | |
| SCHEMBL9665389 | 0.83 | ALDH1A1 (0.54) | ALDH1A1ALOX15RECQLHSD17B10TDP1 | |
| SCHEMBL11046739 | 0.83 | ALDH1A1 (0.54) | ALDH1A1ALOX15RECQLHSD17B10TDP1 | |
| SCHEMBL11946653 | 0.81 | ALDH1A1 (0.52) | ALDH1A1ALOX15RECQLHSD17B10TDP1 | |
| SCHEMBL15609254 | 0.81 | ALDH1A1 (0.52) | ALDH1A1ALOX15RECQLHSD17B10TDP1 | |
| SCHEMBL12494392 | 0.81 | ALDH1A1 (0.52) | ALDH1A1ALOX15RECQLHSD17B10TDP1 | |
| SCHEMBL11858480 | 0.79 | ALDH1A1 (0.43) | ALDH1A1ALOX15RECQLHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10668039-B2 | Methods for treatment of adenoid cystic carcinoma | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2020-06-02 | — | — | US | disclosed |
| US-20190192468-A1 | METHODS FOR TREATMENT OF ADENOID CYSTIC CARCINOMA | THE CHILDREN'S MEDICAL CENTER CORPORATION | 2019-06-27 | — | — | US | disclosed |
| WO-2013174835-A1 | METHODS FOR SCREENING A CANDIDATE COMPOUND FOR ITS PHARMACOLOGY ON A NUCLEAR RECEPTOR | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2013-11-28 | — | — | WO | disclosed |
| US-8048918-B2 | Prevent retinoid binding; antiaging agents; activation cell differentiation | VAMPEX LIMITED (GB) | 2011-11-01 | — | — | US | disclosed |
| US-20030119715-A1 | Treatment of hyperproliferative diseases | VAMPEX LIMITED (GB) | 2003-06-26 | — | — | US | disclosed |
| US-5702914-A | GENETIC ENGINEERING; BIOASSAY | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1997-12-30 | — | — | US | disclosed |