Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.54 |
| ▸ | RECQL | P46063 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | RXRA | P19793 | 8/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.47 |
| ▸ | RARA | P10276 | 5/20 | 0.46 |
| ▸ | RARB | P10826 | 5/20 | 0.46 |
| ▸ | RARG | P13631 | 5/20 | 0.46 |
| ▸ | RXRB | P28702 | 3/20 | 0.46 |
| ▸ | RXRG | P48443 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | RORC | P51449 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HTR2B | P41595 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9665389 | 1.00 | ALDH1A1 (0.54) | ALDH1A1ALOX15RECQLHSD17B10TDP1 | |
| SCHEMBL11046739 | 1.00 | ALDH1A1 (0.54) | ALDH1A1ALOX15RECQLHSD17B10TDP1 | |
| SCHEMBL2579268 | 0.83 | ALDH1A1 (0.59) | ALDH1A1ALOX15RECQLHSD17B10TDP1 | |
| SCHEMBL10952289 | 0.82 | ALDH1A1 (0.52) | ALDH1A1ALOX15RECQLHSD17B10TDP1 | |
| SCHEMBL28352153 | 0.82 | ALDH1A1 (0.52) | ALDH1A1ALOX15RECQLHSD17B10TDP1 | |
| SCHEMBL10952287 | 0.82 | ALDH1A1 (0.52) | ALDH1A1ALOX15RECQLHSD17B10TDP1 | |
| SCHEMBL2616633 | 0.81 | ALDH1A1 (0.83) | ALDH1A1ALOX15RECQLHSD17B10TDP1 | |
| SCHEMBL22506217 | 0.81 | ALDH1A1 (0.83) | ALDH1A1ALOX15RECQLHSD17B10TDP1 | |
| SCHEMBL12494392 | 0.81 | ALDH1A1 (0.52) | ALDH1A1ALOX15RECQLHSD17B10TDP1 | |
| SCHEMBL15609254 | 0.81 | ALDH1A1 (0.52) | ALDH1A1ALOX15RECQLHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0510473-A1 | Thienyl-nonatetraenoic acid derivatives with anti-rheumatic activity | F. HOFFMANN-LA ROCHE AG (CH) | 1992-10-28 | — | — | EP | disclosed |