⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25790194 | 0.85 | — | — | |
| SCHEMBL22461536 | 0.78 | — | — | |
| SCHEMBL25791933 | 0.75 | KDM4E (0.32) | — | |
| SCHEMBL18873139 | 0.73 | — | — | |
| SCHEMBL26048867 | 0.71 | — | — | |
| SCHEMBL26992415 | 0.68 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL23169102 | 0.64 | ALDH1A1 (0.38) | — | |
| SCHEMBL23319054 | 0.63 | — | — | |
| SCHEMBL27383212 | 0.63 | TSHR (0.34) | — | |
| SCHEMBL22349917 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122298-A1 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP28 AND/OR USP25 TARGETING LIGANDS | Stablix, Inc. (US) | 2023-06-29 | — | — | WO | disclosed |