SCHEMBL25791933

SCHEMBL25791933

CNCC(C)(C)OCCC(C)(C)C(=O)NCCCNC(C)C

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CNR1 P21554 1/20 0.32
ARG1 P05089 1/20 0.30
ARG2 P78540 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22349917 0.77
SCHEMBL25792986 0.75
SCHEMBL25790926 0.72 TP53 (0.35) ALDH1A1CNR1
SCHEMBL25880987 0.70 ALDH1A1 (0.41) KDM4EALDH1A1TDP1
SCHEMBL23709094 0.69 ARG1 (0.33) KDM4EALDH1A1TDP1ARG1ARG2
SCHEMBL25851494 0.69 CCR2 (0.32) ALDH1A1
SCHEMBL18736552 0.69
SCHEMBL19366678 0.69 ACHE (0.40) CNR1
SCHEMBL26034150 0.68 CNR1 (0.33) CNR1
SCHEMBL22790789 0.67 CNR1 (0.39) CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023122298-A1 PROTEIN STABILIZING COMPOUNDS CONTAINING USP28 AND/OR USP25 TARGETING LIGANDS Stablix, Inc. (US) 2023-06-29 WO disclosed