Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 3/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.36 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25567786 | 0.82 | P2RX7 (0.45) | P2RX7CNR2HDAC6EPHX2CXCR3 | |
| SCHEMBL25793347 | 0.79 | P2RX7 (0.50) | P2RX7CNR2HDAC6EPHX2CXCR3 | |
| SCHEMBL18085887 | 0.79 | P2RX7 (0.74) | P2RX7CNR2HDAC6CXCR3HDAC4 | |
| SCHEMBL18085886 | 0.71 | HDAC6 (0.56) | P2RX7CNR2HDAC6EPHX2CXCR3 | |
| SCHEMBL18085908 | 0.70 | HDAC6 (0.60) | P2RX7CNR2HDAC6EPHX2CXCR3 | |
| SCHEMBL16021745 | 0.68 | ADRA2A (0.46) | CNR2 | |
| SCHEMBL18085885 | 0.68 | HDAC6 (0.57) | P2RX7HDAC6EPHX2HDAC1HDAC3 | |
| SCHEMBL22680813 | 0.67 | KMT2A (0.38) | CNR2 | |
| SCHEMBL23516584 | 0.66 | KMT2A (0.39) | — | |
| SCHEMBL18997925 | 0.66 | P2RX7 (0.41) | P2RX7HDAC6HDAC4HDAC8HDAC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230212399-A1 | Nonlinear Optical Chromophores Having Short-Chain Bridge Structures, Low Optical Loss Materials Containing the Same, and Methods for Preparing the Same | LIGHTWAVE LOGIC, INC. (US) | 2023-07-06 | — | — | US | disclosed |