Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25793395 | 1.00 | L3MBTL1 (0.53) | L3MBTL1EPHX2GRM5ALDH1A1DGAT1 | |
| SCHEMBL3168186 | 0.87 | DGAT1 (0.58) | L3MBTL1EPHX2ALDH1A1DGAT1SCD5 | |
| SCHEMBL3168169 | 0.87 | DGAT1 (0.58) | L3MBTL1EPHX2ALDH1A1DGAT1SCD5 | |
| SCHEMBL4927632 | 0.86 | L3MBTL1 (0.53) | L3MBTL1EPHX2GRM5DGAT1SCD5 | |
| SCHEMBL4927636 | 0.86 | L3MBTL1 (0.53) | L3MBTL1EPHX2GRM5DGAT1SCD5 | |
| SCHEMBL25793103 | 0.85 | L3MBTL1 (0.49) | L3MBTL1EPHX2GRM5ALDH1A1DGAT1 | |
| SCHEMBL6279671 | 0.85 | NPC1 (0.56) | L3MBTL1EPHX2GRM5DGAT1MEN1 | |
| SCHEMBL6279672 | 0.85 | NPC1 (0.56) | L3MBTL1EPHX2GRM5DGAT1MEN1 | |
| SCHEMBL4924225 | 0.84 | L3MBTL1 (0.50) | L3MBTL1EPHX2GRM5DGAT1PLA2G1B | |
| SCHEMBL4924222 | 0.84 | L3MBTL1 (0.50) | L3MBTL1EPHX2GRM5DGAT1PLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023133507-A1 | ESTRADIOL PRODRUGS AND METHODS OF USE THEREOF | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2023-07-13 | — | — | WO | disclosed |