Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.65 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.49 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12260830 | 0.86 | CHRM1 (0.61) | CHRM1LTB4RLTB4R2MAPK1HPGD | |
| SCHEMBL10269556 | 0.84 | CHRM1 (0.59) | CHRM1LTB4RLTB4R2MAPK1HPGD | |
| SCHEMBL13865331 | 0.80 | CHRM1 (0.55) | CHRM1MAPK1HPGDKMT2AALDH1A1 | |
| SCHEMBL21907373 | 0.78 | CHRM1 (0.56) | CHRM1MAPK1HPGDKMT2AALDH1A1 | |
| SCHEMBL8935862 | 0.78 | KDM4E (0.52) | CHRM1HPGDKMT2AALDH1A1MEN1 | |
| SCHEMBL8935861 | 0.78 | KDM4E (0.52) | CHRM1HPGDKMT2AALDH1A1MEN1 | |
| SCHEMBL13324881 | 0.77 | CHRM1 (0.60) | CHRM1LTB4RLTB4R2MAPK1KMT2A | |
| SCHEMBL13359378 | 0.77 | CHRM1 (0.60) | CHRM1LTB4RLTB4R2MAPK1KMT2A | |
| SCHEMBL11363525 | 0.76 | TSHR (0.63) | CHRM1MAPK1KMT2AALDH1A1MEN1 | |
| SCHEMBL9044655 | 0.74 | KMT2A (0.51) | CHRM1HPGDKMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2399585-A1 | Boronic acids and esters as inhibitors of fatty acid amide hydrolase | Infinity Pharmaceuticals, Inc. (US) | 2011-12-28 | — | — | EP | disclosed |
| EP-2399584-A1 | Boronic acids and esters as inhibitors of fatty acid amide hydrolase | Infinity Pharmaceuticals, Inc. (US) | 2011-12-28 | — | — | EP | disclosed |