Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.46 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13324881 | 1.00 | CHRM1 (0.60) | CHRM1ALOX15HSD17B10L3MBTL1LTB4R | |
| SCHEMBL13324880 | 0.82 | L3MBTL1 (0.51) | CHRM1ALOX15HSD17B10L3MBTL1SLC6A2 | |
| SCHEMBL12173373 | 0.81 | HTT (0.47) | CHRM1GAAMEN1HTTKMT2A | |
| SCHEMBL29516513 | 0.80 | ALOX15 (0.63) | CHRM1ALOX15HSD17B10GAAMEN1 | |
| SCHEMBL13924184 | 0.80 | L3MBTL1 (0.49) | CHRM1ALOX15HSD17B10L3MBTL1SLC6A2 | |
| SCHEMBL257935 | 0.77 | CHRM1 (0.65) | CHRM1ALOX15HSD17B10LTB4RLTB4R2 | |
| SCHEMBL3299127 | 0.77 | PPARG (0.60) | DPP4POLBMEN1HTTKMT2A | |
| SCHEMBL12189840 | 0.77 | PPARG (0.60) | DPP4POLBMEN1HTTKMT2A | |
| SCHEMBL3299728 | 0.77 | PPARG (0.60) | DPP4POLBMEN1HTTKMT2A | |
| SCHEMBL3299123 | 0.77 | PPARG (0.60) | DPP4POLBMEN1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7714131-B2 | Process for the stereoselective preparation of (−)-halofenate and derivatives thereof | METABOLEX, INC. (US) | 2010-05-11 | — | — | US | disclosed |