Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | PPARA | Q07869 | 3/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935861 | 1.00 | KDM4E (0.52) | KDM4EALDH1A1PPARAPPARGNPSR1 | |
| SCHEMBL914217 | 0.93 | PPARG (0.48) | KDM4EALDH1A1PPARAPPARGNPSR1 | |
| SCHEMBL11577533 | 0.87 | PPARG (0.45) | KDM4EALDH1A1PPARAPPARGNPSR1 | |
| SCHEMBL13324879 | 0.87 | KDM4E (0.55) | KDM4EALDH1A1PPARAPPARGMEN1 | |
| SCHEMBL660871 | 0.87 | KDM4E (0.55) | KDM4EALDH1A1PPARAPPARGMEN1 | |
| SCHEMBL21881586 | 0.87 | KDM4E (0.55) | KDM4EALDH1A1PPARAPPARGMEN1 | |
| SCHEMBL11577623 | 0.86 | NPSR1 (0.52) | ALDH1A1PPARAPPARGNPSR1MEN1 | |
| SCHEMBL21881560 | 0.86 | MEN1 (0.58) | KDM4EALDH1A1PPARAPPARGNPSR1 | |
| SCHEMBL5944601 | 0.86 | MEN1 (0.58) | KDM4EALDH1A1PPARAPPARGNPSR1 | |
| SCHEMBL3773899 | 0.85 | KDM4E (0.53) | KDM4EALDH1A1PPARAPPARGNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491167-A | INHIBITORS OF CHOLESTEROL BIOSYNTHESIS | SANKYO COMPANY, LIMITED (JP) | 1996-02-13 | — | — | US | disclosed |