Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 14/20 | 0.40 |
| ▸ | PGR | P06401 | 5/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.37 |
| ▸ | AR | P10275 | 3/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488782 | 0.73 | AHR (0.42) | AHRNR3C1PGRBCHE | |
| SCHEMBL15499617 | 0.71 | ATM (0.37) | AHRNR3C1PGRNR3C2AR | |
| SCHEMBL7864768 | 0.69 | AHR (0.48) | AHRNR3C1PGRKEAP1NR3C2 | |
| SCHEMBL21149281 | 0.67 | AHR (0.46) | AHRNR3C1PGRKEAP1NR3C2 | |
| SCHEMBL29469161 | 0.67 | AHR (0.42) | AHRNR3C1PGRKEAP1NR3C2 | |
| SCHEMBL2028185 | 0.67 | AHR (0.42) | AHRNR3C1PGRKEAP1NR3C2 | |
| SCHEMBL9946124 | 0.65 | NPSR1 (0.41) | — | |
| SCHEMBL31637123 | 0.65 | CYP3A4 (0.48) | — | |
| SCHEMBL9688985 | 0.65 | AHR (0.47) | AHRNR3C1PGRKEAP1NR3C2 | |
| SCHEMBL4882951 | 0.64 | HTR2C (0.49) | AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2399585-A1 | Boronic acids and esters as inhibitors of fatty acid amide hydrolase | Infinity Pharmaceuticals, Inc. (US) | 2011-12-28 | — | — | EP | disclosed |