SCHEMBL21149281

SCHEMBL21149281

c1cc(C2CCCC2)c2[nH]ccc2c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 2/20 0.46
KEAP1 Q14145 1/20 0.41
PDPK1 O15530 1/20 0.40
TRPA1 O75762 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
ITGB2 P05107 1/20 0.38
ICAM1 P05362 1/20 0.38
ITGAL P20701 1/20 0.38
CA4 P22748 1/20 0.38
CA6 P23280 1/20 0.38
ADK P55263 1/20 0.38
NR3C1 P04150 1/20 0.37
PGR P06401 1/20 0.37
NR3C2 P08235 1/20 0.37
AR P10275 1/20 0.37
ADORA1 P30542 1/20 0.36
PDK2 Q15119 4/20 0.36
PDK4 Q16654 2/20 0.36
BACE1 P56817 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7864768 0.92 AHR (0.48) AHRKEAP1PDPK1TRPA1CA1
SCHEMBL4882951 0.86 HTR2C (0.49) AHR
SCHEMBL31389946 0.79 AHR (0.43) AHRKEAP1PDPK1TRPA1CA1
SCHEMBL30437530 0.73 MEN1 (0.44) AHRKEAP1PDPK1BCHE
SCHEMBL14027792 0.70 HTR1A (0.47) AHRBCHE
SCHEMBL8995183 0.69 HTR1A (0.48) AHRBCHE
SCHEMBL497994 0.68 SLC6A4 (0.56)
SCHEMBL14337309 0.68 BACE1 (0.43) AHRKEAP1PDPK1NR3C1PGR
SCHEMBL779938 0.67 CHRNB4 (0.46) BCHE
SCHEMBL2140203 0.67 KEAP1 (0.49) AHRKEAP1PDPK1NR3C1PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019135600-A1 NOVEL METAL COMPLEX, METHOD FOR PRODUCING SAME, AND METHOD FOR PRODUCING GAMMA-LACTAM COMPOUND USING SAME 기초과학연구원 2019-07-11 WO disclosed