Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 4/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23816601 | 0.78 | CYP1A2 (0.42) | MAPTSMN1; SMN2CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL9505783 | 0.71 | ALDH1A1 (0.55) | MAPTCYP1A2CYP2C19ALDH1A1MEN1 | |
| Methylamine SCHEMBL28262977 | 0.71 | CYP1A2 (0.46) | MAPTCYP1A2CYP2C19ALDH1A1MEN1 | |
| SCHEMBL5167762 | 0.70 | ALDH1A1 (0.59) | MAPTSMN1; SMN2CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL28539089 | 0.67 | CYP1A2 (0.42) | MAPTCYP1A2CYP2C19ALDH1A1MEN1 | |
| SCHEMBL11546049 | 0.66 | CYP1A2 (0.44) | MAPTSMN1; SMN2CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL1229448 | 0.66 | ESR1 (0.71) | MAPTSMN1; SMN2CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL11511323 | 0.66 | ALDH1A1 (0.48) | MAPTCYP1A2CYP2C19ALDH1A1MEN1 | |
| SCHEMBL10235441 | 0.66 | CYP2C19 (0.47) | SMN1; SMN2CYP1A2CYP2C19ALDH1A1GAA | |
| SCHEMBL10162939 | 0.66 | EPHX2 (0.45) | CYP1A2CYP2C19ALDH1A1HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230212143-A9 | PRMT5 INHIBITOR COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2023-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230212143-A9 | PRMT5 INHIBITOR COMPOUNDS | PRMT5, PRMT1, PRMT6 | MAPT 1665/4885SMN1; SMN2 342/4885CYP1A2 3883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.