⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25794279 | 0.85 | STK17A (0.37) | — | |
| SCHEMBL25794271 | 0.81 | STK17B (0.34) | — | |
| SCHEMBL13532079 | 0.62 | TAAR1 (0.61) | — | |
| SCHEMBL10850136 | 0.61 | MAPT (0.45) | — | |
| SCHEMBL21318995 | 0.58 | RAB9A (0.40) | — | |
| SCHEMBL9189354 | 0.57 | CNR2 (0.49) | — | |
| SCHEMBL9737481 | 0.56 | AOC3 (0.45) | — | |
| SCHEMBL7855536 | 0.56 | CYP2C19 (0.53) | — | |
| Hydrochloric Acid SCHEMBL9457584 | 0.56 | CNR2 (0.48) | — | |
| Hydrochloric Acid SCHEMBL9518394 | 0.55 | AOC3 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122298-A1 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP28 AND/OR USP25 TARGETING LIGANDS | Stablix, Inc. (US) | 2023-06-29 | — | — | WO | disclosed |