⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18245458 | 0.85 | TSHR (0.35) | — | |
| SCHEMBL4646638 | 0.78 | TSHR (0.30) | — | |
| SCHEMBL1070324 | 0.76 | CYP1A2 (0.32) | — | |
| Hydrochloric Acid SCHEMBL5862019 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL2237708 | 0.74 | CYP1A2 (0.31) | — | |
| SCHEMBL3336535 | 0.72 | TRPA1 (0.31) | — | |
| SCHEMBL156371 | 0.69 | — | — | |
| SCHEMBL20428108 | 0.69 | — | — | |
| SCHEMBL539979 | 0.69 | — | — | |
| SCHEMBL1457234 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1531851-B1 | COVALENT CONJUGATES BETWEEN ARTEMISININ-RELATED ENDOPEROXIDES AND IRON-CARRYING PROTEINS AND METHODS OF USE | UNIV WASHINGTON (US) | 2011-12-14 | — | — | EP | disclosed |
| US-8048850-B2 | Anticancer agents | UNIVERSITY OF WASHINGTON (US) | 2011-11-01 | — | — | US | disclosed |
| EP-1531851-A4 | COVALENT CONJUGATES BETWEEN ARTEMISININ-RELATED ENDOPEROXIDES AND IRON-CARRYING PROTEINS AND METHODS OF USE | UNIV WASHINGTON (US) | 2007-12-12 | — | — | EP | disclosed |
| US-20070104939-A1 | Cleaning sheets, transfer member having cleaning function, and method of cleaning substrate-processing apparatus with these | NITTO DENKO CORPORATION | 2007-05-10 | — | — | US | disclosed |
| CN-1313145-C | Covalent conjugates between artemisinin-related endoperoxides and iron-carrying proteins and methods of use | UNIV WASHINGTON (US) | 2007-05-02 | — | — | CN | disclosed |
| CN-1668323-A | Covalent conjugates between artemisinin-related endoperoxides and iron-carrying proteins and methods of use | UNIV WASHINGTON (US) | 2005-09-14 | — | — | CN | disclosed |
| EP-1531851-A2 | COVALENT CONJUGATES BETWEEN ARTEMISININ-RELATED ENDOPEROXIDES AND IRON-CARRYING PROTEINS AND METHODS OF USE | UNIVERSITY OF WASHINGTON (US) | 2005-05-25 | — | — | EP | disclosed |
| US-20040067875-A1 | Covalent conjugates between artemisinin-related endoperoxides and iron-carrying proteins and methods of use | UNIVERSITY OF WASHINGTON | 2004-04-08 | — | — | US | disclosed |
| WO-2003103592-A2 | COVALENT CONJUGATES BETWEEN ARTEMISININ-RELATED ENDOPEROXIDES AND IRON-CARRYING PROTEINS AND METHODS OF USE | UNIVERSITY OF WASHINGTON (US) | 2003-12-18 | — | — | WO | disclosed |