Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 3/20 | 0.45 |
| ▸ | CDC7 | O00311 | 1/20 | 0.31 |
| ▸ | F12 | P00748 | 1/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | NCF1 | P14598 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25794814 | 1.00 | NNMT (0.45) | NNMTCDC7F12PLAUNCF1 | |
| SCHEMBL25795081 | 1.00 | NNMT (0.45) | NNMTCDC7F12PLAUNCF1 | |
| SCHEMBL25794820 | 0.81 | NNMT (0.46) | NNMT | |
| SCHEMBL25794964 | 0.77 | NNMT (0.46) | NNMT | |
| SCHEMBL31720967 | 0.77 | NNMT (0.48) | NNMT | |
| SCHEMBL25794824 | 0.77 | NNMT (0.48) | NNMT | |
| SCHEMBL25794827 | 0.76 | NNMT (0.36) | NNMTCDC7NOS3NOS2 | |
| SCHEMBL25794825 | 0.75 | NNMT (0.44) | NNMT | |
| SCHEMBL25255431 | 0.72 | NNMT (0.44) | NNMT | |
| SCHEMBL25794812 | 0.72 | NNMT (0.41) | NNMTF12PLAUNCF1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023129513-A2 | BICYCLIC HETEROAROMATIC INHIBITORS OF NICOTINAMIDE N-METHYLTRANSFERASE, AND COMPOSITIONS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-07-06 | — | — | WO | disclosed |