Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 3/20 | 0.48 |
| ▸ | PI4KA | P42356 | 2/20 | 0.33 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.33 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31720967 | 1.00 | NNMT (0.48) | NNMTPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL30428054 | 0.72 | NNMT (0.44) | NNMT | |
| SCHEMBL25255431 | 0.72 | NNMT (0.44) | NNMT | |
| SCHEMBL13686454 | 0.67 | LIMK1 (0.40) | NNMTRETLRRK2LIMK1 | |
| SCHEMBL25426494 | 0.67 | NNMT (0.47) | NNMT | |
| SCHEMBL18681127 | 0.64 | NNMT (0.43) | NNMT | |
| SCHEMBL25425826 | 0.63 | NNMT (0.58) | NNMT | |
| SCHEMBL25425830 | 0.63 | NNMT (0.58) | NNMT | |
| SCHEMBL25425377 | 0.61 | NNMT (1.00) | NNMT | |
| SCHEMBL25426347 | 0.61 | NNMT (0.56) | NNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023129513-A2 | BICYCLIC HETEROAROMATIC INHIBITORS OF NICOTINAMIDE N-METHYLTRANSFERASE, AND COMPOSITIONS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-07-06 | — | — | WO | disclosed |