Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 3/20 | 0.55 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 2/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.31 |
| ▸ | PARP11 | Q9NR21 | 5/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14498838 | 0.78 | NNMT (0.59) | NNMTUHRF1DRD1PARP10PARP11 | |
| SCHEMBL7213850 | 0.78 | NNMT (0.55) | NNMTUHRF1DRD1PARP10PARP11 | |
| SCHEMBL7214252 | 0.75 | NNMT (0.53) | NNMTUHRF1DRD1PARP10PARP11 | |
| SCHEMBL25787743 | 0.71 | NNMT (1.00) | NNMTDRD1PARP10PARP11 | |
| SCHEMBL580706 | 0.71 | NNMT (0.37) | NNMTDRD1GRM5 | |
| SCHEMBL12605346 | 0.70 | NNMT (0.55) | NNMTUHRF1DRD1PARP10PARP11 | |
| SCHEMBL16195616 | 0.68 | NNMT (0.45) | NNMTUHRF1 | |
| SCHEMBL795294 | 0.67 | DRD1 (0.49) | NNMTUHRF1DRD1GRM5 | |
| SCHEMBL30159359 | 0.67 | DRD1 (0.49) | NNMTUHRF1DRD1GRM5 | |
| SCHEMBL795352 | 0.67 | NNMT (0.44) | NNMTUHRF1DRD1PARP10PARP11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023129513-A2 | BICYCLIC HETEROAROMATIC INHIBITORS OF NICOTINAMIDE N-METHYLTRANSFERASE, AND COMPOSITIONS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-07-06 | — | — | WO | disclosed |