Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 3/20 | 0.55 |
| ▸ | PARP10 | Q53GL7 | 6/20 | 0.35 |
| ▸ | PARP11 | Q9NR21 | 6/20 | 0.35 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 2/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16195616 | 0.89 | NNMT (0.45) | NNMTUHRF1 | |
| SCHEMBL25795779 | 0.78 | NNMT (0.55) | NNMTPARP10PARP11UHRF1DRD1 | |
| SCHEMBL14498838 | 0.78 | NNMT (0.59) | NNMTPARP10PARP11UHRF1DRD1 | |
| SCHEMBL13996732 | 0.78 | NNMT (0.55) | NNMTPARP10PARP11GRM5 | |
| SCHEMBL1368910 | 0.76 | NNMT (0.35) | NNMT | |
| SCHEMBL7214252 | 0.75 | NNMT (0.53) | NNMTPARP10PARP11UHRF1DRD1 | |
| SCHEMBL13991574 | 0.75 | PARP10 (0.42) | NNMTPARP10PARP11DRD1GRM5 | |
| SCHEMBL12146612 | 0.74 | NNMT (0.38) | NNMTPARP10PARP11 | |
| SCHEMBL25787743 | 0.71 | NNMT (1.00) | NNMTPARP10PARP11DRD1 | |
| SCHEMBL12605346 | 0.70 | NNMT (0.55) | NNMTPARP10PARP11UHRF1DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610692-B1 | Anticoagulants | MERCK & CO., INC. | 2003-08-26 | — | — | US | disclosed |
| EP-1124822-A4 | THROMBIN INHIBITORS | MERCK & CO INC (US) | 2002-04-03 | — | — | EP | disclosed |
| EP-1124822-A1 | THROMBIN INHIBITORS | Merck & Co., Inc. (US) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026211-A1 | THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2000-05-11 | — | — | WO | disclosed |