Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25789870 | 0.75 | NNMT (0.55) | NNMT | |
| SCHEMBL25424023 | 0.74 | NNMT (0.56) | NNMT | |
| SCHEMBL25426347 | 0.74 | NNMT (0.56) | NNMT | |
| SCHEMBL25426494 | 0.74 | NNMT (0.47) | NNMT | |
| SCHEMBL25924181 | 0.64 | RAF1 (0.34) | GAA | |
| SCHEMBL25323587 | 0.63 | GAA (0.36) | GAA | |
| SCHEMBL4745297 | 0.61 | SRC (0.51) | — | |
| SCHEMBL4745279 | 0.61 | EGFR (0.38) | — | |
| SCHEMBL4745298 | 0.61 | SRC (0.51) | — | |
| SCHEMBL4745277 | 0.61 | EGFR (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023129513-A2 | BICYCLIC HETEROAROMATIC INHIBITORS OF NICOTINAMIDE N-METHYLTRANSFERASE, AND COMPOSITIONS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-07-06 | — | — | WO | disclosed |