Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25322849 | 0.82 | ALDH1A1 (0.32) | RAF1GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL25323587 | 0.82 | GAA (0.36) | GAAALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL22120693 | 0.76 | GRIA1 (0.35) | GAAALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL13773302 | 0.70 | HTT (0.40) | GAAALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL2982328 | 0.70 | HTT (0.40) | GAAALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL3828343 | 0.70 | HTT (0.40) | GAAALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL3559922 | 0.69 | TSHR (0.41) | RAF1ALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL15334774 | 0.69 | TSHR (0.44) | RAF1ALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL30481365 | 0.67 | HTT (0.40) | GAAALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL1550437 | 0.67 | HTT (0.40) | GAAALDH1A1MAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146990-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |