Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 4/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.38 |
| ▸ | RAD52 | P43351 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31054273 | 0.98 | GRM5 (0.44) | GRM5F10F2RAD52RECQL | |
| SCHEMBL3007282 | 0.84 | GRM5 (0.45) | GRM5F10F2RAD52RECQL | |
| SCHEMBL114205 | 0.75 | RAD52 (0.63) | GRM5RAD52RECQLNPC1RAB9A | |
| SCHEMBL5776887 | 0.74 | GRM5 (0.47) | GRM5F10F2RAD52RECQL | |
| Bromide SCHEMBL1253502 | 0.73 | RAD52 (0.61) | GRM5RAD52RECQLNPC1RAB9A | |
| SCHEMBL209848 | 0.73 | GRM5 (0.51) | GRM5F10F2RAD52RECQL | |
| SCHEMBL8051769 | 0.73 | GRM5 (0.51) | GRM5F10F2RAD52RECQL | |
| SCHEMBL9096033 | 0.73 | APOBEC3A (0.50) | GRM5NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL25797005 | 0.72 | ALOX15 (0.45) | GRM5F10F2NPC1RAB9A | |
| SCHEMBL765133 | 0.72 | F10 (0.49) | GRM5F10F2HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116812-A1 | SULFONYLUREA COMPOUND | 瑞石生物医药有限公司 | 2023-06-29 | — | — | WO | disclosed |